Mission: To improve health through innovative research and collaboration. Vision: To be a nationally recognized partner in primary care research. Values: Patient-centered, Inclusive, Engaging, Relevant, Rigorous The Family Medicine Research team’s areas of expertise include interventions such as shared decision making to improve disparities in patient outcomes, clinical trials with impact to address health disparities, implementation science, population health and informatics, and social determinants of health. We also provide research and scholarship opportunities to residents, medical school students and other learners who are interested in primary care research or public health. |
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The Family Medicine Research Team can be reached at 704-304-7100 or at: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mercy Medical Plaza | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2001 Vail Avenue, Suite 400B | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Charlotte, NC 28207 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Research Team
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Hazel Tapp, PhD Dr. Tapp currently serves as Director of Research in the Department of Family Medicine at Atrium Health, at the Center for Primary Care Research. Her research interests are broadly centered in improving health disparities and increasing health equity. This includes implementing improved delivery of care for patients with chronic diseases such as sickle cell disease, HIV, hepatitis C, diabetes, and asthma. As co-director of a practice-based research network (PBRN), the Mecklenburg Area Partnership for Primary Care Research, she works on several projects designed to use community based participatory research (CBPR) and implementation research to study improved outcomes for populations with chronic disease through implementation of evidence-based interventions. As PI on a PCORI patient-centered outcomes research institute project designed to study the dissemination of shared decision making using participatory implementation strategies, Dr. Tapp worked with 4 Practice-based research networks and Medicaid across North Carolina to implement shared decision making for asthma patients across 30 practices and in the Emergency Department. Also, in partnership with community members, patients, community organizational representatives, providers, and other research team members, Dr. Tapp helped develop and actively serve as a participating member of several community advisory boards (CABs) and patient advisory board (PAB). Dr Tapp is nationally involved in primary care research leadership, serving as Chair and Board Member of the North American Primary Care Research Group (NAPCRG) Program Committee. NAPCRG’s annual conference is attended by over 1200 primary care researchers from around the world and is considered the leading global General Practitioner and Family Medicine research conference. During the COVID-19 pandemic Dr Tapp is organizing a stakeholder advisory group for community outreach and recruitment on a CDC funded COVID-19 surveillance study and a qualitative study to evaluate provider perspectives on COVID-19 experiences |
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Lindsay E. Shade, MHS, PA-C
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Thomas Ludden, PhD Thomas serves as the Director of Population Health and Data Analytics and has worked with the Department of Family Medicine for 13 years. His research interests include health outcomes research utilizing geospatial models and providing data analytics and study design around patient health outcomes for various studies related to improvements in outcomes for chronic diseases. He has collected and analyzed patient outcomes primarily for patients with diabetes and asthma and provides expertise in designing the appropriate databases to answer proposed research questions. He has also provided extensive guidance around analytics for examining the screening rates for Hepatitis C and HIV. His professional goals include increasing capacity to examine health outcomes data through utilizing electronic medical records to capture patient level information. |
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David Price, MD Dr. Price’s research interests include concussion, pre-participation athletic screening and sudden cardiac death in athletes. Diagnosis and management of concussion currently relies mainly on subjective criteria rather than objective criteria. Currently we are investigating an objective tool to aid in concussion diagnosis and return to play. We currently host a large pre-participation annual screening event for athletes in the surrounding community which provides a unique opportunity to capture data on athletes regarding depression, blood pressure, cardiac status, and obesity. Pre-participation screening of athletes serve as a valuable opportunity to screen for depressive symptoms given its increasing prevalence in adolescence. Cardiovascular screening in young athletes is also widely recommended prior to participation in competitive sports. While there is general agreement that early detection of cardiac conditions at risk for sudden cardiac arrest and death (SCA/D) is an important objective, the optimal strategy for cardiovascular screening in athletes remains an issue of considerable debate. Dr. Price, on behalf of American Medical Society for Sports Medicine, helped author a Position Statement on Cardiovascular Pre-participation Screening in Athletes: Current evidence, knowledge gaps, recommendations, and future directions. This work has been published in the British Journal of Sports Medicine. Family Medicine Research Summer 2023 Newsletter
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Current Research Studies
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Key Publications
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SURPASS-CVOT - is a diabetes study designed to examine the cardiovasular (CV) protective capabilities of Tirzepatide, a GLP-1 receptor agonist. This is a Phase 3 clinical trial that will assess the effect of once weekly Tirzepatide vs. Dulaglutide (Trulicity) on (CV) outcomes when added to standard of care in Type II Diabetes Mellitus patients with established CV disease. The study is expected to follow patients for 5 to 6 years.
We are currently enrolling patients at Atrium Health Family Medicine and Internal Medicine practices through February 2022. Eligible patients are 40 or over with Type II Diabetes and secific CV risk factors.
Sponsor: Eli Lilly
PI: Dr. Jewell Carr
Research Team: Andrea Price, Amanda Balasco, Faith Ellerbe, Lindsay Shade
CAPTURE - Undiagnosed COPD is a leading cause of morbidity and mortality. Spirometry, the ‘gold standard’ for diagnosis, is not recommended for screening in asymptomatic individuals and remains widely underutilized in primary care settings. Through a simple tool using five questions combined with selective peak expiratory flow measurement, the study seeks to identify individuals suffering from undiagnosed ‘clinically significant’ COPD so they can be treated, resulting in improved health status, reduced exacerbations and decreased morbidity.
To date, we have enrolled 842 patients from 19 practices!
Pl: Hazel Tapp, PhD
Research Team: Andrea Price, Marina Leonidas, Katherine O'Hare, Cody Oliver, Jeremy Thomas, Lindsay Shade
COLOGUARD - The primary objective of the main study, 2019-01, is to test an updated version of Cologuard against the colonoscopy gold standard. The primary objective of the sub-study, 2019-01B, is to collect blood specimens for research use in the development and validation of a blood-based test for colorectal cancer (CRC).
The study is open for enrollment of patients scheduled for screening colonoscopies at Atrium Health endoscopy centers. We have currently enrolled 24 patients.
PI: Dr. Jewel Carr
Research Team: Amanda Balasco, Faith Ellerbe, Jeremy Thomas, Lindsay Shade
PREVENTABLE - is a landmark study of statins in older adults. The study will enroll 20,000 participants from 100 sites across the US. We know statins are effective for reducing the risk of cardiovascular events in individuals with cardiovascular disease and up to age 75 without disease, but limited evidence proves the usefulness of statins for primary prevention in adults over age 75, especially in the setting of multiple chronic conditions. We are hoping to learn if taking a statin (atorvastatin 40 mg vs placebo) could help older adults live well longer by preventing dementia, disability or cardiovascular disease.
Current enrollment = 24
PI: Lindsay Shade, PA-C
Research Team:Faith Ellerbe, Amanda Balasco, Cody Oliver, Dr. Tony Caprio
Elizabeth Family Medicine Patient Advisory Board (PAB)
Presenting at national conferences and serving on conference committees allows our Family Medicine Research team to showcase current projects to broader research communities. This networking exposure and sharing of ideas also invites greater team recognition and more opportunities for future research collaborations.
Hazel Tapp, PhD, described the use of a community participatory approach to engage stakeholders to guide our recruitment and data collection efforts for a COVID-19 surveillance study aimed at learning about the spread of the virus in local communities and among healthcare workers.
Tom Ludden, PhD, presented an evaluation of HIV screening to compare pre and post EMR alert activation along with a peer-to-peer educational program. Data was summarized by practice type and race and results showed differing improvement levels based on those data groupings.
Andrea Price showcased how our team of research coordinators were charged with creating strategies to proactively reach out to participants to improve communication, participation, and overall participant satisfaction with the COVID-19 surveillance study. Their efforts and ideas were instrumental in study success as it rolled out on a national level.
Kelly Reeves presented work-in-progress on a study to examine primary care providers' perceived barriers and facilitators to virtual visit utilization during the COVID-19 pandemic. Focusing on 4 community-based primary care clinics, the initial phase of the study used cross-sectional surveys emailed to eligible study participants.